![]() ![]() Lucky For Life Drawings take place every day at 10:35pm ET. To win Lucky For Life top prize of $1,000 a day for life, Lucky For Life players need to match the 5 white balls and Lucky Ball. ![]() Lucky For Life Players choose five white balls numbered from 1-48 and one Lucky Ball from 1-18 plus the number of drawings to enter. Draws take place every Tuesday and Friday at 11pm ET. The top prize is won by matching 5 white balls and the Mega Ball. For an additional cost, Mega Millions players can add Megaplier for the chance to multiply their lottery winnings.Īlternatively, Mega Millions players can just select ‘Just the Jackpot’ which gives you two chances at winning the jackpot prize only. Mega Millions players choose five white balls numbered from 1-70 and one Mega Ball from 1-25, then choose the number of Mega Millions drawings to play. Drawings take place on a Monday, Wednesday and Saturday at 11pm ET. Wins are awarded for matching just white balls or a combination of white balls and the Power Ball.įor an additional $1 per play, you can add Power Play to multiply your Kentucky lottery winnings. Players choose five numbers from 1-69 (white balls) and one Power Ball from 1-26, then select the number of drawings you wish to play at $2 per draw. The Cash Pop draw takes place daily, every four minutes. ![]() The top prize, based on a $10 wager, is $2,500. Players choose up to 15 numbers from 1-15, select how many consecutive draws they wish to participate in and decide their wager from $1, $2, $5 or $10 per number. The Keno draw takes place every four minutes on a daily basis, and you can check your draws online or at a local authorized retailer. The top Keno prize could reach as high as $100,000. For an additional cost, you can add a multiplier and bullseye for more chances to win bigger Kentucky lottery prizes. Players choose up to 10 lottery numbers from 1-80, decide on how many consecutive draws to enter and set their base wager. Kentucky Lottery Games and Drawing Schedule Keno Players can also take advantage of the latest online promotions including a 30% Match Deposit and Refer A Friend deals. With a registered account you can buy tickets for all draw games plus over 40 Instant Play games and 70+ Scratch-offs. For convenience, you may wish to download the mobile app for iOS (Apple) or Android devices. Yes, KY Lottery tickets can be purchased from the official website once you have registered an online account. Winning tickets are valid for up to 180 days from the date of the draw. Kentucky Lottery tickets can be purchased from any licensed retailer or online through the Kentucky Lottery’s official website once you have registered an account. There are specific terms and conditions which apply to the various games offered by the Kentucky Lottery Corporation, but these are the general rules in order to participate.
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![]() ![]() “It’s important to come up with a safe signal before you start having sex,” says Tyomi Morgan-Najieb, a certified sexologist and pleasure coach. One thing is important about these positions, though. And you don’t have to change what you’re doing all that much to reap the benefits of this sexy act. But there are actually a ton of different positions that change the way oral sex feels for both the giver and the receiver. It usually involves sitting in a chair and letting your partner take over, or laying down on the bed with your partner positioned between your legs. “This gives both partners vaginal access and allows the receiver to direct their own experience by maintaining control of their hips without having to support their own weight,” she says.There’s a common misconception that, when it comes to oral sex positions, there isn’t a ton of variety. “One of the best positions for DVP is to have the receiving partner kneeling over one of the giving partners, at the edge of a bed, while the second giving partner’s standing behind the receiver,” says Neal. Physically, because their phallus gets to enjoy the tightness of a vagina *and* the sensation of another phallus rubbing against it.Īnd psychologically, because DVP often involves power-exchange between the penetrators and the receiver. It can be both physically and psychologically arousing for the penetrators as well. “They may also be psychologically aroused by the thought of being filled by two phalluses (two penises, one penis and one strap-on, or two strap-ons) inside of them at the same time,” she adds. “DVP allows a vagina-haver to experience a lot of sensation, fullness, and pressure inside their vagina,” says Neal. In case you don’t know: DVP = double vaginal penetration. Could any first-aid supplies be necessary?.What snacks and drinks do you want to have on hand?.Who will be doing the toy and sheet clean-up?.“But sex toys can add in more options for play and pleasure, and make sure that everyone can have something fun happening to their body if hands, tongues, and genitals are otherwise occupied.” Noted! Talk about post-sex needs, pre-playīefore the threesome starts, you want to negotiate what’s going to happen when the threesome ends, says queer sex educator Marla Renee Stewart, MA, sexpert for Lovers, an adult wellness brand and retailer. “What toys you use will depend on personal preferences, and what everyone is comfortable doing and to whom,” says Deysach. The longer the sex session goes on, the less likely the body is able to produce ample lubrication to keep the session enjoyable, explains Searah Deysach, sex educator and owner of Early to Bed, a pleasure-product company in Chicago that ships worldwide.Īdding in store-bought lubrication ensures that any bumping and grinding remains pleasurable instead of getting friction-y. Are there other boundaries or concerns?ĭo threesome quickies exist? Sure! But if you’re reading a list of the best threesome positions, odds are the threesome in your horizon won’t be one.Īnd while it’s well-documented that all sex is made more pleasurable by lube, lube is especially important for lengthy love-making.Are some people just watchers, or are there boundaries around certain sex acts with certain people?.What is everyone’s level of involvement?.What sexy things are on the menu and which ones are off the menu?.What’s been your previous experience with threesomes?.What barriers do we want to use for what sex acts?.To manage expectations and ensure the most pleasurable experience for all parties, Matatas says it’s important to ask and answer the following before stripping down: Communicate about what the threesome is going to look like beforehand ![]() It can feature vaginal intercourse, anal intercourse, both the types of intercourse simultaneously, or a mix. It can include hand sex, oral sex, solo sex, or a mix. So let the record show that a threesome doesn’t need to include penetration to qualify as a threesome.Ī threesome is, simply, sex that happens between three people, says sexuality, body, confidence, and kink educator Luna Matatas, creator of Peg The Patriarchy.Īnd that sex can be many different expressions of pleasure! Porn may have led you to believe that threesomes are all about penetration and double penetration. Remember how expansive the definition of threesomes really is These five tips will set yourself up for pleasure, regardless of position. ![]() ![]() Please include your ip address, the time you received this message and what you were doing at the time. Campfires generate light that prevent wandering overworld Ghosts in Graveyards and Deep. You can reach us at management (at) e621 (dot) net You will need to contact us to have it removed. Find and team up with nearby players, discover new areas, and send messages across all Niantic games. Some features of Campfire can be found directly in Niantic’s games but for the most. The software first became available in 2022 for select users, but its more widely available in 2023. If none of the above apply to you, then you have likely been blocked manually after review. Campfire is a new feature that lets you play your favorite Niantic games with your local community. In other words, Campfire is a social smartphone application that connects to Pokémon GO and lets you find other trainers to team up with for a Raid. But there are also some things you might not. There's a lot of Pokemon to meet and different things to try, so take your time and have fun with it This game is fun if you explore it and find some of the surprises for yourself. If you repeatedly see this message you should stop all access attempts and contact us so that the problem can be resolved. Here's a puzzle game I made where you can interact and solve puzzles with Pokemon. #4 Something else, probably abusive behavior Please see the wiki page for the API for additional details. The default user agent for many programming languages and libraries have been blocked for abuse.ĭO NOT USE A BROWSER USER AGENT FOR API TOOLS - YOU WILL GET MANUALLY BLOCKED. If you are attempting to use the API you may be seeing this if your user agent is not in line with our user agent policy. Please contact the author, or find another, more up to date tool. You likely can't resolve this problem yourself, as the application you are using needs to be updated. ![]() Do not use some random "documentation" you found on github, it is out of date and incorrect. Please visit the wiki for the most up to date information. If you are making requests to endpoints that are not plurals, then you fall under this category. You need to update your application to use the new API urls and response formats. As the result of no shared code between the old and new site, the API changed, both in response format and urls. We updated our codebase quite drastically in March 2020. Something else, I've checked the above 3 and they don't apply to me.Your applications user agent is incorrectly configured.You are using an outdated program that makes use of bad practices or old API endpoints.the US camera and social media company that develops technological products and services. You have not updated your application to use the new API urls and response formats. Incoming search terms: Pokemon pocket campfire all animation itch. ![]() There are a few different reasons that you can run into this message: ![]() It's great, and probably does what you want! 403 Access Denied - Oh no! If you were using a script/program you found to try and download content, it's likely that the script was what resulted in your request being blocked. ![]() ![]() ![]() ![]() High-resolution solution structure of the 18 kDa substrate-binding domain of the mammalian chaperone protein Hsc70. Substrate specificity of the DnaK chaperone determined by screening cellulose-bound peptide libraries. Rudiger, S., Germeroth, L., Schneider-Mergener, J. Peptide binding and release by proteins implicated as catalysts of protein assembly. Common and divergent peptide binding specificities of hsp70 molecular chaperones. The novolactone natural product disrupts the allosteric regulation of Hsp70. Identification of an allosteric pocket on human hsp70 reveals a mode of inhibition of this therapeutically important protein. Identifying and characterizing binding sites and assessing druggability. Characterization of a lidless form of the molecular chaperone DnaK: deletion of the lid increases peptide on- and off-rate constants. Molecular basis for interactions of the DnaK chaperone with substrates. Hsp70 chaperones are non-equilibrium machines that achieve ultra-affinity by energy consumption. Mechanism of regulation of hsp70 chaperones by DnaJ cochaperones. DnaJ dramatically stimulates ATP hydrolysis by DnaK: insight into targeting of Hsp70 proteins to polypeptide substrates. Multistep mechanism of substrate binding determines chaperone activity of Hsp70. ![]() An interdomain energetic tug-of-war creates the allosterically active state in Hsp70 molecular chaperones. The specialized Hsp70 (HscA) interdomain linker binds to its nucleotide-binding domain and stimulates ATP hydrolysis in both cis and trans configurations. Allosteric signal transmission in the nucleotide-binding domain of 70-kDa heat shock protein (Hsp70) molecular chaperones. Allosteric regulation of Hsp70 chaperones involves a conserved interdomain linker. Pathways of allosteric regulation in Hsp70 chaperones. Kityk, R., Vogel, M., Schlecht, R., Bukau, B. ![]() Structural analysis of substrate binding by the molecular chaperone DnaK. The peptide-binding domain of the chaperone protein Hsc70 has an unusual secondary structure topology. Three-dimensional structure of the ATPase fragment of a 70K heat-shock cognate protein. The remarkable multivalency of the Hsp70 chaperones. The nucleotide exchange factors of Hsp70 molecular chaperones. Hierarchical functional specificity of cytosolic heat shock protein 70 (Hsp70) nucleotide exchange factors in yeast. The HSP70 chaperone machinery: J proteins as drivers of functional specificity. Widespread proteome remodeling and aggregation in aging C. The detection and role of heat shock protein 70 in various nondisease conditions and disease conditions: a literature review. Hsp70 - a master regulator in protein degradation. R., Gragera, M., Ochoa-Ibarrola, L., Quintana-Gallardo, L. Cellular handling of protein aggregates by disaggregation machines. Hsp70 at the membrane: driving protein translocation. Protein disaggregation in multicellular organisms. In vivo aspects of protein folding and quality control. This knowledge showcases how the Hsp70 chaperone system controls diverse cellular functions, and offers new opportunities for the development of chemical compounds that modulate disease-related Hsp70 activities.īalchin, D., Hayer-Hartl, M. In this Review we describe recent advances that have increased our understanding of the molecular mechanisms and working principles of the Hsp70 network. Moreover, Hsp70s cooperate with other cellular chaperone systems including Hsp90, Hsp60 chaperonins, small heat shock proteins and Hsp100 AAA+ disaggregases, together constituting a dynamic and functionally versatile network for protein folding, unfolding, regulation, targeting, aggregation and disaggregation, as well as degradation. A large set of co-chaperones comprising J-domain proteins and nucleotide exchange factors regulate the ATPase cycle of Hsp70s, which is allosterically coupled to substrate binding and release. They function virtually at all stages of the life of proteins from synthesis to degradation and are thus crucial for maintaining protein homeostasis, with direct implications for human health. The 70-kDa heat shock proteins (Hsp70s) are ubiquitous molecular chaperones that act in a large variety of cellular protein folding and remodelling processes. ![]() ![]() With it, you can restore lost data for free now without even using a license code. 2GB Free Data Recovery, No License Code RequiredĮaseUS free data recovery software - Data Recovery Wizard Free Edition enables you to restore 500MB data for free by default.īy click the share button in the wizard and share to Facebook or Twitter, you can obtain 2GB of free recovery capacity. Here the following, you'll get two options to obtain official license code or serial key of EaseUS Data Recovery Wizard for fast and reliable data recovery. 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![]() OL6220731W Page_number_confidence 75.55 Pages 248 Ppi 300 Republisher_date 20191128101917 Republisher_operator Republisher_time 1277 Scandate 20191126074620 Scanner Scanningcenter cebu Scribe3_search_catalog isbn Scribe3_search_id 0689858833 Tts_version 3. Urn:lcp:bluestreasuryofs0000unse:epub:53e616da-52d1-4136-a07a-11f6577e0bc0 Foldoutcount 0 Identifier bluestreasuryofs0000unse Identifier-ark ark:/13960/t0vr11v3k Invoice 1652 Isbn 0689858833ĩ780689858833 Ocr ABBYY FineReader 11.0 (Extended OCR) Ocr_converted abbyy-to-hocr 1.1.20 Ocr_module_version 0.0.16 Old_pallet IA15468 Openlibrary_edition Blues Big treasure Hunt leads us to unlock doors we have not seen before and leads us to skidoo into a special land. ![]() Access-restricted-item true Addeddate 04:00:35 Associated-names Santomero, Angela C Peltzman, Adam Wilder, Alice Smith, Michael T Reber, Deborah Boxid IA1707607 Camera USB PTP Class Camera Collection_set printdisabled External-identifier ![]() ![]() “Again, be careful-you don’t want to seem like you’re only applying because the company offers great work-life balance. – You’re seeking better work-life balanceĮmployers are increasingly sensitive to the demands of millennials, working parents, caregivers, and others who want a healthier work-life blend.īeing upfront-not pushy-about the importance of work-life integration is a great comeback to questions about why you’re leaving your current job. Talk about the specific requirements of the position and how your background makes you a good fit. Here’s where you can elaborate on the skills that have gotten you this far (to the interview stage) in the hiring process. Get specific and offer a litany of reasons why you’re tailor-made for the job. – You believe the prospective employer’s job opening is a great fit for your skills and experience This forward-thinking approach signals a maturity and level-headedness that could be appealing to a potential employer. Put yourself in a good light by presenting yourself as a highly responsible job candidate who’s willing and capable of taking on even more. – You want to take on more responsibility You’re looking for a place where you can grow with the company, not just the next step in your rise to the top,” suggest the Career Experts. “A key to this response is connecting your career advancement with helping to advance the company at the same time. Follow up by saying that, in your experience, your current job doesn’t allow for the kind of advancement you’re seeking. Put a long-term spin on your answer by explaining that your overall career goals include achieving a specific job level or title in your profession. Avoid describing your current job as “dead-end,” which may come across as bad-mouthing your current employer. ![]() Use the opportunity to talk about your professional skills and how you’re looking for fresh challenges in your career that make the most of your abilities. And don’t speak badly about your less-than-flexible current or past employers.” – You’re looking for new challenges Talk about how flexible work helps you be more productive and creative, or specifically how it’s helped your work in the past. You don’t want a prospective employer to think you’re only in it for the flexibility. The FlexJobs Career Expert team advises, “Be careful with this one, though. ![]() The “why are you leaving your current job” question can open the door for you to talk about any past success working remotely, your technical know-how in operating from your home office, and your steadfast dedication to flexible work. ![]() How to answer, “Why are you leaving your current job?” – You’re looking for greater work flexibility The cost of losing employees and hiring and training new ones is high, and companies want to feel like you’re applying to their job for the right reasons.īe prepared to answer this question with confidence to boost your chances of getting hired. They’re also likely trying to assess if you’re an employee who will stick with the company and align with its mission. Employers asking this question are trying to uncover your motivation for finding a new job, and in particular, why you want leave your current role and work for them. One of the most tough interview questions is when employers want to know, “Why are you leaving your current job?”ĭon’t let that question stymie you. As a job seeker, you can minimize your jitters by being prepared for the kinds of questions you might be asked. A job interview can be a nerve-wracking experience, but it doesn’t have to be. ![]() ![]() ![]() ![]() Ultrasonographic examination of the chest readily identified pathological changes consistent with severe lung pathology subsequently confirmed as chronic suppurative pneumonia in four cows at necropsy eight cows recovered well after antibiotic treatment and were discharged two to six weeks after admission. All cattle were tachypnoeic (>40 breaths per minute) with frequent and productive coughing, halitosis, and a purulent nasal discharge most noticeable when the head was lowered. Most cows (8/12) had a normal rectal temperature on presentation but all cows had received antibiotic therapy at some time in the previous two weeks and six animals were receiving antibiotic treatment upon admission. Twelve cows, referred to the University of Edinburgh Veterinary School, were diagnosed with chronic suppurative pneumonia and enrolled into this prospective study to record and monitor lung sounds, ultrasonographic findings, and response to a standardised antibiotic treatment regimen. ![]() Simultaneous recording of sounds overlying normal lung and defined pathology allows critical assessment of auscultated sounds in the same animal removing confounding factors such as respiratory rate and thickness of the chest wall (body condition). Modern portable ultrasound machines provide the veterinary practitioner with an inexpensive, non-invasive tool with which to examine the pleural surfaces and superficial lung parenchyma. Consolidation is often a middle-to-late stage feature/complication in pulmonary infections.Auscultation is considered the critical component of the veterinary clinical examination for the diagnosis of bovine respiratory disease but the accuracy with which adventitious sounds reflect underlying lung pathology remains largely unproven. Consolidated tissue is more radio-opaque than normally aerated lung parenchyma, so that it is clearly demonstrable in radiography and on CT scans. Typically, an area of white lung is seen on a standard X-ray.A lower P AO 2 than calculated in the alveolar gas equation.Here, the patient's voice (or whisper, as in whispered pectoriloquy) can be heard more clearly when there is consolidation, as opposed to the healthy lung where speech sounds muffled. Possible medium, late, or pan-inspiratory crackles.Percussion note is impaired in the affected area.Vocal fremitus is increased on the affected side.Expansion of the thorax on inspiration is reduced on the affected side. ![]() Signs that consolidation may have occurred include: Consolidation must be present to diagnose pneumonia: the signs of lobar pneumonia are characteristic and clinically referred to as consolidation. The liquid can be pulmonary edema, inflammatory exudate, pus, inhaled water, or blood (from bronchial tree or hemorrhage from a pulmonary artery). Consolidation occurs through accumulation of inflammatory cellular exudate in the alveoli and adjoining ducts. The condition is marked by induration (swelling or hardening of normally soft tissue) of a normally aerated lung. B: Abnormal chest X-ray with consolidation from pneumonia in the right lung, middle or inferior lobe (white area, left side of image).Ī pulmonary consolidation is a region of normally compressible lung tissue that has filled with liquid instead of air. Medical condition Pulmonary consolidation ![]() ![]() ![]() New-hire orientation (recommended but not required). It is important for employees to be aware of the new job designation tasked to them and the expectations of the business towards their performance as well. It provides fair compensation and extensive benefits during orientation period while also promoting a unified professional appearance through dress code guidelines. A new employee orientation program checklist can ensure the business that the program for new hires is a combination of fun and responsibility introduction. Family Care and Medical Leave Fact Sheet Target Orientation is an essential process that introduces new employees to the organization, its regulations and workplace expectations. ![]() You can also find a ton of information and resources within the student handbook. If you have any questions along the way, please contact our Admissions Counselors at 606.539.4240. Other information can direct you to the orientation process and answer questions about living on campus. Before collecting personal information from an applicant or employee. This starts the process of getting you on campus. New-hire orientation (if not included in the employee handbook) and when an employee asks about or requests parental leave. Rights of Victims of Domestic, Sexual Assault and Stalking ![]() New-hire orientation (applies to non-exempt employees only). 1, 2022, in addition to physically displaying required posters in the workplace. Introduction of coworkers, teams, and supervisors. Orientation programs generally include: A tour of the workplace. This usually happens during their first few days of employment. In a response to the trend of allowing employees to work remotely, California will permit employers to distribute required notices and posters to employees by email, effective Jan. Depending on your organization and the team member’s job functions, new employee orientation typically includes some or all of the following: Filling out health insurance, tax and other paperwork. Work Orientation is when newly hired employees are welcomed to their new workplace and introduced to their job, company, work environment, and colleagues. While the forms listed below are mandated by state laws, an employer may require additional forms to be completed by new hires based on company policy. This checklist provides an overview of California’s state notices that must be provided to newly hired employees. ![]() ![]() ![]() The formula to calculate the perimeter of an isosceles triangle is P = 2a + b where 'a' is the length of the two equal sides and 'b' is the base of the triangle.Since an isosceles triangle has two equal sides, its perimeter can be calculated if the base and the equal sides are known.A triangle is considered to be an isosceles triangle if it has two equal sides.Here is a list of a few points that should be remembered while studying the perimeter of an isosceles triangle: ![]() ![]() Important Notes on Perimeter of Isosceles Triangle It should be noted that the two congruent angles in the isosceles right triangle measure 45° each. When the hypotenuse is given: Referring to the explanation given above, if the hypotenuse (h) is given, then the perimeter of an isosceles right triangle will be (P) = h + 2(h/√2) = h + √2h = h(1 + √2).When the length of the equal side is given: Referring to the explanation given above, if the length (l) is given, then the perimeter of an isosceles right triangle will be (P) = 2l + (√2)l = (2 + √2)l.These values can be substituted with each other if one of them is not known. This means h = √2 × l, which can also be written as: l = h/√2. If we apply the Pythagoras theorem in the figure, we get h = √(l 2+ l 2) = √2 × l. Now, let us find the perimeter of an isosceles right triangle in 2 different scenarios given below. Observe the following figure to understand the dimensions and the formula of an isosceles right triangle.Īs given in the figure, the perimeter of an isosceles right triangle is P = h + 2l. If the length of the hypotenuse is 'h' units and the lengths of the other two sides are 'l', then the perimeter of an isosceles right triangle would be: Perimeter of isosceles right triangle = h + l + l. Since it is a right-angled triangle, one of its sides is the hypotenuse and the other two sides are equal. The perimeter of an isosceles right-angled triangle can be found by adding the length of all its three sides. ![]() |
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